Biotin and its role in a healthy life

Research Based
Medically reviewed by - Dr Lara Mokhtar, MD Written by - Dr. Diksha Sangle


What is Biotin ?

A water-soluble vitamin called biotin, also referred to as vitamin H or vitamin B7, is necessary for the body to process carbs, lipids, and amino acids properly.1Overview | Researched based study from

Multivitamins, B-vitamin complexes, and standalone supplements all include biotin. Good bacteria of our lumen also produce biotin. It can also be found in trace amounts in a variety of foods. Biotin is also important for normal embryonic growth, making it a critical nutrient during pregnancy.

A water-soluble vitamin called biotin, referred to as vitamin H or vitamin B7 is necessary for the body to process carbs, lipids, and amino acids properly.


Facts about biotin

  • The vitamin biotin was first identified in 1931 as promoting good skin and hair in rats.
  • Additionally, it has shown anti-inflammatory and antioxidant qualities.
  • Biotin is not retained by our body .
  • Since biotin was initially obtained from egg yolks, which were known in German as “Haar and Haut,” or “hair and skin,” biotin is sometimes referred to as “Vitamin H.”
  • The term “biotin deficiency facies” refers to the rash and oddly distributed face fat in those who are biotin deficient.


Biological functions for Biotin.

Biological functions

Metabolism of energy

  • The metabolism of proteins, carbs, and lipids is necessary. It plays a role in transforming these macronutrients into cellular energy that the body can utilize.

Expression of genes

  • Controlling the expression of specific genes necessary for cellular development and division plays a function in gene expression.3Functions | Researched based study from

The health of the skin, hair, and nails.

  • Maintaining good skin, hair, and nails depends on it. Keratin, a protein that makes up these structures, is produced in its support.3Functions | Researched based study from

Nervous system function

  • The normal functioning of the neurological system depends on biotin. It participates in the production of neurotransmitters and myelin, a substance that protects nerve fibers and aids in transmitting nerve impulses.3Functions | Researched based study from

Immune system function

  • It has been shown to have immuno-modulating effects, which means it can aid in controlling the immune response and defending against illness and infection.

Fetal growth

  • The development of the nervous system, in particular, depends on biotin during foetal life.3Functions | Researched based study from

Blood sugar control

  • Enhances insulin sensitivity and cell uptake of glucose, which helps to control blood sugar levels.3Functions | Researched based study from

Health Benefits

Benefits for health 

Type 1 Diabetes

  • Biotin has been demonstrated to increase insulin sensitivity and glucose uptake in cells, which may help control blood sugar levels in people with type 1 diabetes.4Benefits | Researched based study from

Reduced inflammation

  • It contains anti-inflammatory qualities and could aid in reducing bodily inflammation, which is associated with several chronic disorders.

Enhanced mental capacity

  • It might aid in promoting healthy brain function and enhancing cognitive abilities.

Decreased chance of birth abnormalities

  • Reduces the chance of birth abnormalities, especially when the neurological systemis developing. 2Health benefits | Researched based study from


What are the dietary sources?


  • Egg yolks
  • Organ meats (such as liver and kidney)
  • Dairy products (cheese, yoghurt)
  • Meat (beef and chicken)
  • Fish and shellfish (mackerel, salmon and oysters).1Sources | Researched based study from


  • Nuts and seeds (such as almonds, peanuts, and sunflower seeds)
  • Legumes (such as beans, lentils, and soybeans)
  • Whole grains (such as wheat germ and whole wheat bread)
  • Fruits (such as bananas and raspberries)
  • Vegetables (such as sweet potatoes, spinach, and broccoli).1Sources | Researched based study from


Deficiency symptoms of Biotin

  • Hair loss: Hair loss, hair thinning and colour loss, is one of the most prevalent symptoms.
  • Skin rash: A biotin deficit may result in a scaly, red rash around the mouth, nose, and genital region.
  • Brittle nails: This condition may also result in nails that are easily broken or split.
  • Fatigue: Because of its involvement in metabolism, it can cause fatigue and weakness.
  • Neurological symptoms: A deficiency may result in neurological symptoms like seizures, depression, and tingling in the hands and feet.
  • Cramping and muscle soreness are both possible.
  • Increased vulnerability to infections due to impaired immune function.5Symptoms | Researched based study from


Causes of Biotin deficiency

Poor diet

A diet deficient in foods rich in biotin, such as may cause the deficit.

Prolonged use of few medicines

  • Antibiotics  The gut flora balance can be upset by antibiotics, which might affect the body’s ability to produce biotin.
  • Anti-epileptics and anti-convulsant these drugs inhibit renal reabsorption of biotin and also enhance the rate of biotin catabolism 6Causes | Researched based study from

Genetic disorders

  • The body’s capacity to absorb and utilize biotin can be compromised by a few uncommon diseases, such as biotinidase deficiency.6Causes | Researched based study from

Breastfeeding and pregnancy

  • They have a higher need, and a shortfall could arise if they consume more biotin-rich foods or supplements.

Digestive disorders

  • The body’s ability to absorb biotin can be hampered by conditions like Crohn’s disease, celiac disease, and inflammatory bowel disease.


  • Alcohol abuse might affect metabolism and absorption over time.


  • Smokers may have low biotin levels and necessitate biotin supplement.


  • Patients undergoing renal dialysis may have low amounts of biotin and require a biotin supplement.

Eating raw egg whites

  • A protein called avidin is found in raw egg whites and attaches to biotin to stop it from being absorbed.5Causes | Researched based study from


Biotin overdose toxicity

The body eliminates biotin through the urine. As a result, biotin overdose is uncommon and usually not a problem for healthy people. High doses, however, may have some adverse effects, such as:

  • Skin breakout
  • Skin rash and acne
  • Supplements taken in high doses have been shown to interfere with lab testing, especially thyroid and hormone tests, producing inaccurate results.
  • Nausea, diarrhea, and cramps are all symptoms of an upset stomach.
  • An allergic reaction may result in symptoms like hives, breathing difficulties, and itching.


Recommended dosage

According to the National Institutes of Health (NIH), the following RDAs for biotin:

For infants

  • 0-6 months: 5 mcg/day
  • 7-12 months: 6 mcg/day 1Dosage | Researched based study from

For children

  • 1-3 years: 8 mcg/day
  • 4-8 years: 12 mcg/day
  • 9-13 years: 20 mcg/day
  • 14-18 years: 25 mcg/day1Dosage | Researched based study from

For adults who are

  • 19 years and older: 30 mcg/ day

For pregnant women

  • 35 mcg/day

Breastfeeding women

  • 35-40 mcg/day 1

Adults should not exceed the acceptable upper intake level of 1000 mcg per day, and significant dose supplements should only be used under a doctor’s supervision.1Dosage | Researched based study from


Interaction with medicines


  • Anticonvulsant drugs like phenytoin and carbamazepine may hamper absorption.7Interactions| Researched based study from


  • Tetracycline and sulfa medications, two common antibiotics, can cause interference.8Interactions| Researched based study from

Acne treatments

  • The drug isotretinoin may affect metabolism, which is used to treat severe acne.9Interactions| Researched based study from


  • Medicines that can affect metabolism include cyclosporine.
Disclaimer: The user acknowledges that this article's information is being offered for informational purposes only. Every attempt has been made to guarantee that the article is informational and correct. If they have any doubts or questions about their health, we firmly advise our readers to visit a doctor or other healthcare professional.

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