Bromelain: Exploring the Benefits and Uses

Research Based
Medically reviewed by - Dr. MESSANGA Dimitri, MD Written by - Dr. Diksha Sangle


What is Bromelain ?

The pineapple stem and berries contain the natural enzyme bromelain. It is a member of the proteolytic class of enzymes that break down proteins. 1Overview | Researched based study from

Indigenous South Americans have long used it as a supplement. For medicinal purposes, it has become more well-known as a dietary supplement in recent years because of its possible health advantages.

A versatile enzyme with many possible health advantages is Bromelain. We will learn more about its applications, dosage, side effects, and risks in this piece.

The pineapple stem and berries contain the natural enzyme bromelain. It is a member of the proteolytic class of enzymes that break down proteins.


How is Bromelain helpful to us?

How is Bromelain helpful to us?

Reduces inflammation

  • It has been discovered to possess potent anti-inflammatory qualities, which could aid in reducing swelling and inflammation in the body. Because of this, it can be used to treat illnesses like osteoarthritis, rheumatoid arthritis, and athletic injuries.1Benefits | Researched based study from

Improves digestion

  • Additionally, it helps with metabolism. It is understood that breaking down proteins in the intestines enhances nutrient absorption.
  • Studies have also indicated that Bromelain may help ease digestive disorder symptoms like gas and bloating. 2Benefits| Researched based study from

Boosts immunity

  • It has immune-boosting qualities that could enhance general health and reduce the chance of infections.
  • Cytokines are proteins involved in the immune reaction, and it has been demonstrated that this substance stimulates their production. 1Benefits | Researched based study from

Anticancer properties.

  • Bromelain may have anticancer properties and help lower the risk of developing certain kinds of cancer. In vitro and animal studies have shown that it inhibits the growth of cancer cells, but additional study is required to confirm these results. 4Benefits | Researched based study from

Reduces the severity of the allergy and asthmatic symptoms

  • Additionally, it might lessen how bad allergies and asthma problems are. It might aid in reducing the airway inflammation linked to these illnesses.


  • In a study conducted, Bromelain was found to be effective in alleviating the symptoms of chronic rhino sinusitis including swelling and congestion. 9Benefits | Researched based study from

Promotes the healing of wounds

  • It has been discovered that lowering inflammation and boosting blood flow to the wounded region can aid wound healing. In some studies, it has been applied topically to heal burns and other injuries. 3Benefits | Researched based study from

It may have cardiovascular benefits.

  • According to studies, Bromelain may help the heart by lowering the chance of blood clots and promoting circulation. It has been discovered to have anti-thrombic and antiplatelet traits, which may aid in preventing blood clots. 5Benefits| Researched based study from

Adverse effects

What are the adverse effects?

Even though Bromelain is typically considered safe for most people when consumed properly, some people may experience some side effects. These are a few adverse effects:

Digestive issues

  • Some individuals may suffer nausea, diarrhea, or upset stomach when taking Bromelain. 7Adverse effects | Researched based study from


Some individuals may experience allergic reactions. Possible signs include 6Adverse effects | Researched based study from

  • Itching
  • Hives
  • Cheeks, lips, or tongue swelling
  • Having trouble breathing
  • Chest constriction

Increased heartbeat

  • Some people may experience a rise in heart rate as a result.

Menstrual bleeding

  • It might make some women’s menstrual flow heavy.

A skin reaction

  • Taking Bromelain may cause a skin rash in some individuals.

Dry Mouth

  • Often seen as a side effect in people taking bromelain supplements.

It is crucial to remember that the list of side effects is not comprehensive and that additional side effects could manifest. 7Adverse effects | Researched based study from


Who is at risk while using Bromelain?


  • A greater risk of an allergic reaction may exist in those allergic to latex, grass pollen, carrot, wheat, celery, or pineapple.

Bleeding issues

  • In individuals with blood disorders or those taking blood-thinning medications, it may have an anti-coagulant effect and raise the chance of bleeding.

Intestinal problems

  • People with conditions like gastritis, ulcers, or inflammatory bowel disease (IBD) must take care because it could worsen things. 6Contraindications| Researched based study from

During Pregnancy

  • There is no conclusive evidence from scientific studies that eating pineapple causes miscarriages or any other ill effect on pregnancy. 10Contraindications| Researched based study from

During Breastfeeding

  • Little of research on bromelain’s safety during breastfeeding is available. Hence, its supplements should also be avoided by breastfeeding women. 11Contraindications| Researched based study from

Before surgery

  • If combined with other medications that influence coagulation, it may increase the risk of bleeding. So, those who are considering surgery should refrain from consuming bromelain for at least two weeks before the procedure. 10Contraindications| Researched based study from


Does Bromelain interact with other medicines?

Certain medicines, such as blood thinners, antibiotics, and anti-inflammatory drugs, may interact with it. Before using a supplement, discussing any potential interactions with your doctor or chemist is essential. The following are a few drugs that might interact:

Clotting agents

  • The chance of bleeding rises when combined with blood thinners like aspirin, warfarin, or heparin. 8Interactions | Researched based study from


  • Bromelain should be taken at least two hours before or after taking antibiotics because it may affect how well some antibiotics, like doxycycline and amoxicillin, are absorbed.

Anti-inflammatory drugs

  • It is advised to exercise care because it may intensify the effects of anti-inflammatory drugs like ibuprofen or naproxen. 8Interactions | Researched based study from


  • It might intensify the effects of sedatives like barbiturates, benzodiazepines, anti-seizure medicines, anti-depressants and alcohol. 8Interactions | Researched based study from

Chemotherapy medications

  • It might combine with some chemotherapy medications and lessen their efficiency. 8Interactions | Researched based study from


Dosage and Forms

There are several ways to get Bromelain, including

  • Capsules
  • Tablets
  • Powder
  • Creams.

The most popular supplement form is in the shape of a capsule or tablet. Powders can be consumed orally by combining them with water or other liquids. 7Dosage | Researched based study from

The dosage and form may change depending on the planned use and specific requirements. The following are some basic principles:

Correct dosage for consumption

  • 500–1000 mg daily is frequently advised for mild inflammation and overall digestive health.
  • A higher dosage of up to 2000–3000 mg daily is recommended for more severe inflammation or pain. 7Dosage | Researched based study from


  • Depending on the form and your particular preferences, it can be taken without food or between meals. Some types are applied topically to the epidermis, like creams or gels.


Key Takeaways

  • Bromelain has anti-inflammatory properties and is used to treat many conditions.
  • Supplements are available in many forms and can be purchased at health food stores or online.
  • It is essential to remember that self-treating with Bromelain supplements instead of living without treatment for medical conditions can have adverse outcomes.
  • Talk to your healthcare provider before consuming it, especially if taking other medications.
Disclaimer: The user acknowledges that this article's information is being offered for informational purposes only. Every attempt has been made to guarantee that the article is informational and correct. If they have any doubts or questions about their health, we firmly advise our readers to visit a doctor or other healthcare professional.

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