Bydureon BCise: Uses, Side effects and Precautions

Research Based
Medically reviewed by - Dr Rabia Akram, MD Written by - Dr. Diksha Sangle


What is the Bydureon BCise?

Bydureon BCise is a medicine made by AstraZeneca that is an advanced therapy option made primarily to cater to the demands of people with type 2 diabetes. It provides a practical and patient-friendly method of managing diabetes.1Overview| Researched based study from

We shall examine the numerous facets of this medication in this article, including its applications, dosage, adverse effects, etc.

Bydureon BCise is a medicine made by AstraZeneca that is an advanced therapy option made primarily to cater to the demands of people with type 2 diabetes. It provides a practical and patient-friendly method of managing diabetes.


Uses of Bydureon BCise

  • Blood sugar control in type 2 diabetics
  • In weight management
  • Promotes good heart health
  • It can be used along with other antidiabetic medicines

It is primarily used in the direction of type 2 diabetes. Here are the critical uses and benefits:

Blood sugar management

  • It helps those with type 2 diabetes manage their blood sugar levels. It helps lower HbA1C levels and reduces the risk of complications by enhancing glycemic control.1Uses| Researched based study from

Weight control

  • It has been linked to weight loss in diabetics. It helps reduce hunger, slows gastric emptying, and promotes a sense of fullness. For those who are overweight or obese, the weight loss impact can be advantageous because it improves insulin sensitivity and metabolic health in general.

Decrease in cardiovascular risk

  • There is evidence from studies that it can enhance heart health It has been linked to lower levels of inflammatory markers, cholesterol, and blood pressure. These support the general health of the cardiovascular system.1Uses| Researched based study from

Combination therapy

  • It can be taken on its own or with other antidiabetic drugs. It can supplement the effects of other oral medications or insulin therapy to obtain the best glycemic control. When other treatments alone are not sufficient to regulate blood sugar, this approach may be taken into account.2Uses| Researched based study from

How does it work?

  • Bydureon BCise contains the hormone exenatide, which helps in blood sugar regulation. It mimics a hormone your body naturally makes when you inject it. It slows digestion, increases the amount of insulin your pancreas releases, and lowers the amount of sugar your liver produces.
  • Stable blood sugar levels and improved diabetes management are made possible by all of this1Uses| Researched based study from

Bydureon BCise Vs Bydureon

What separates Bydureon BCise from Bydureon?

The main difference lies in their formulation and method of administration

Bydureon bcise

  • A once-weekly injectable medication supplied in a pen device with prefilled needles. It has an extended-release formulation; thus, it releases gradually over time in the body.
  • Patients can administer it more conveniently because it is injected beneath the skin using a pen instrument.
  • Dosage is given once each week.


  • It is formulated as a powder that must be reconstituted before administration and is packaged in a vial.
  • It is injected subcutaneously using a needle and syringe and requires a reconstitution step.
  • One dose every two weeks is recommended.2Bydureon BCise Vs Bydureon| Researched based study from


How should I use the Bydureon BCise Pen?

Taking the dose

  1. The pen needs to be taken out of the refrigerator and left to come to room temperature. Confirm the liquid in the pen is clear and free of impurities, as well as the expiration date.
  2. If the liquid contains particles or is discolored, do not use the pen.
  3. Allow the injection site to dry after cleaning it with an alcohol swab.
  4. Remove the pen cap and release the covering tab to reveal the needle. Tap the pen lightly while holding it upright to eliminate any air bubbles.
  5. Pinch a fold of skin where it has been cleaned. Hold the pen in your other hand while you angle the needle at a 45-degree angle and fully penetrate the skin that has been squeezed.
  6. Thoroughly press the button until you hear it click. Keep pressing it firmly for at least 10 seconds to guarantee the entire amount is administered.
  7. Put the pen cap back on and discard it properly2Dosage| Researched based study from

Injection sites

  • Choose an area at least two inches from your belly button on your abdomen (middle of your stomach). Avoid touching your waistband or beltline.
  • Choose a spot on the front of the thigh that is 4 inches below the top of the leg and 4 inches above the knee.
  • It’s essential to change the injection site regularly. Aim for a minimum of one inch between locations close to one other. By doing this, pain or skin reactions are reduced.2Dosage| Researched based study from

Side effects

Side effects of Bydureon BCise.

Side effects of Bydureon BCise

Mild side effects

  • Nausea
  • Diarrhea
  • Injection site reactions like bumps
  • Hypoglycemia
  • Pancreatitis

Serious side effects

  • Kidney damage
  • Thyroid tumors
  • Pancreatitis
  • Gallbladder issues

It’s important to keep in mind that not everyone may have these side effects, and some may even be unusual. The typical ones linked are as follows:2Side effects| Researched based study from


  • Some people may have mild to moderate nausea, especially at the start of treatment. As the body becomes used to the medication, this typically improves over time.


  • Some may get diarrhea or loose stools as a result. By getting adequate water and eating a balanced diet, you can prevent this.

Reactions at the site of the injection

  • The area where the injection was given can be swollen, itchy, or red.
  • These reactions typically subside on their own and are moderate. Using the proper technique and switching up the locations might lessen the discomfort.


  • A higher risk of hypoglycemia has been connected to BCise, not just Bydureon. Additionally, taking two or more diabetes drugs together increases the risk of low blood sugar.


  • It has occasionally been linked to pancreatitis or pancreatic inflammation. If you have severe abdominal pain, seek medical help.

Thyroid cancer

  • People taking Bydureon BCise have been reported to develop thyroid tumors, including thyroid cancer. It’s critical to be aware of any new neck lumps or swelling and to contact your doctor right away.

Kidney issues

  • Some patients may experience kidney function issues. You are at risk if you have a history of renal issues.

Gall bladder issues

  • Acute events such as cholelithiasis and cholecystitis have been reported in some patients.


What needs to be taken into account before taking Bydureon BCise?

Discuss medical history

  • Tell your doctor about your health, including current diseases like pancreatitis, thyroid issues, kidney disease, or liver disease.

Talk about Allergies

  • If you have any known allergies or hypersensitivity, let your doctor know.

Pregnancy and breastfeeding

  • It’s essential to address the pros and cons with your doctor if you’re breastfeeding, pregnant, planning to become pregnant, or both. Alternative treatment options may be sought because their safety during pregnancy or breastfeeding has not been shown.2Precautions| Researched based study from

Kidney issues

  • Close monitoring and dose adjustments are required in patients with renal impairment consuming Bydureon Bcise. This is done to avoid complications, including hypovolemia, a condition where there is a decrease in extracellular fluid of the body.3Precautions| Researched based study from

Injection technique

  • Ensure you get the right guidance on the proper injection method, and pay close attention to the directions.

Diet and lifestyle

  • Any dietary or lifestyle adjustments that may be required to support the effectiveness of the medication should be discussed with your doctor2Precautions| Researched based study from


Overdose toxicity of Bydureon BCise

Symptoms of hypoglycemia may include:

  • Sweating
  • Dizziness
  • Confusion
  • Rapid heartbeat
  • Trembling
  • Weakness
  • Fainting

It is advised to ingest a source of glucose, such as a sweet beverage or glucose tablets if you feel any of these symptoms.

Always adhere to your doctor’s recommendations for proper use and dosage to avoid an overdose. Ask your doctor for advice on when to take the next dose if you miss one. Avoid taking two doses at once to make up for the missing amount2Overdose| Researched based study from


Medication interaction

The risk of hypoglycemia may be increased by using insulin or other antidiabetic medications in combination. It may be essential to alter the dosage or closely check the blood sugar levels.

Oral diabetic medications

  • When combined with Bydureon BCise, some medications, such as Sulfonylureas, Meglitinides, or DPP-4 inhibitors, may have additive effects on blood sugar control.

Prescription drugs that affect gastrointestinal motility

  • The effect of absorption of drugs that affect gastric motility, such as anticholinergic drugs or drugs for GI diseases, may change. For specific advice, speak with your healthcare physician4Interactions| Researched based study from

Drugs that damage the pancreas

  • The effectiveness of Bydureon BCise may be affected by medications that have pancreatic effects, such as glucocorticoids or octreotide.2Interactions| Researched based study from
Disclaimer: The user acknowledges that this article's information is being offered for informational purposes only. Every attempt has been made to guarantee that the article is informational and correct. If they have any doubts or questions about their health, we firmly advise our readers to visit a doctor or other healthcare professional.

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