Thyroid Peroxidase Antibodies (TPO)
Analyzer Report
Related Thyroid Test Analyzer
Frequently Asked Questions
Autoantibodies termed thyroid peroxidase antibodies (TPO antibodies) attack thyroid peroxidase, an enzyme necessary for the synthesis of thyroid hormones. Blood tests that detect TPO antibodies often reveal the existence of autoimmune thyroid conditions such Hashimoto’s thyroiditis or Graves’ disease.
When antibodies against the thyroid peroxidase enzyme are low, the TPO (thyroid peroxidase) count is low. Hypothyroidism, or an underactive thyroid gland, is most frequently caused by Hashimoto’s thyroiditis. If your TPO count is low, it may mean that you are less likely to develop autoimmune thyroid disease, including Hashimoto’s thyroiditis.
Thyroid peroxidase (TPO) levels over normal are often indicative of Hashimoto’s thyroiditis, an autoimmune condition. The existence of these antibodies, as shown by a high TPO count, is definitive evidence of the autoimmune origin of the illness.
TPO antibody count, also known as TPO antibody titer or level, is a method for determining how many TPO antibodies are floating about in a person’s blood. An increased immune reaction to thyroid peroxidase is often reflected in elevated levels of TPO antibodies.
TPO antibody testing can help doctors diagnose and keep tabs on autoimmune thyroid conditions. High levels of TPO antibodies have also been linked to an increased chance of developing thyroid dysfunction, even in those with normal amounts of thyroid hormone. Thyroid peroxidase antibody titers should be interpreted in the context of other clinical signs and laboratory testing, including thyroid hormone levels (T3, T4, and TSH), for an accurate picture of the patient’s thyroid condition.
