Thyroid stimulating immunoglobulin (TRAb) is the blood marker for this hormone. Thyroid stimulating immunoglobulin (TSI) is an antibody that causes the thyroid to generate too much thyroid hormone. Antibody against the thyroid hormone receptor (TRAb).

Having fewer of these stimulating antibodies present is indicated by a low TRAb count. Several explanations are listed below:

● When the TRAb count drops, it may signal that a person who once had Graves’ illness is now in remission.

● Treatment for Graves’ disease, including anti-thyroid medication, radioactive iodine therapy, and surgery, might reduce TRAb production or activity, hence a low TRAb count may be indicative of effective treatment.

Thyroid autoimmunity, especially Graves’ disease, is commonly accompanied with an increased TRAb count. In Graves’ disease, the immune system generates TSI in error, which binds to thyroid gland receptors and stimulates hyperthyroidism. Since TRAb levels can give insight into the severity of Graves’ illness and the responsiveness to therapy, they are frequently employed in the diagnosis and monitoring of the disease.