Letrozole, also known by the brand name Femara, is a non-steroidal aromatase inhibitor medicine It is a hormonal treatment medicine that has received FDA approval and is frequently used, especially in postmenopausal women, to manage hormonally sensitive breast cancer.

The drug letrozole is used for treating:

• Hormone receptor-positive early breast cancer in postmenopausal women receiving adjuvant therapy.
• Extensive adjuvant therapy is advised for postmenopausal women with early breast cancer who have already undergone standard adjuvant tamoxifen therapy.
• For postmenopausal women who have breast cancer that is progressed and either hormone receptor positive or undetermined.

Like all medications, Letrozole may cause specific side effects. The most typical negative effects include:

• Hot flushes
• Fatigue
• Headaches
• Hair loss
• Depression

Letrozole may increase the risk of the following:

• Allergy – If you’ve ever experienced an allergic response to Letrozole or any inactive chemicals in Femara, you shouldn’t use it.
• Liver injury – People with liver disorder should discuss it with the doctor as Letrozole is eliminated from the system by the liver; people might require a reduced dosage of Femara.
• Bone loss – Letrozole may raise an individual’s chance of developing bone conditions, including osteoporosis.
• High cholesterol risk – Some people who take Letrozole may experience elevated cholesterol levels and may require ongoing monitoring.